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In preclinical research models, MT-2 has been characterized for its agonism at MC1R (the receptor governing melanocyte eumelanin synthesis) and at MC4R (a central receptor studied in energy-homeostasis and melanocortin-signaling research)

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Some patients may use it for 6-12 months to achieve a new, stable baseline of immune function, while many others choose to stay on a maintenance dose long-term to keep the autoimmune process in remission

Oral semaglutide likewise resulted in reductions in weight during the trial