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We think that the [neurons influence] on intervertebral disc degeneration is not only limited to the occurrence of pain, but also intervertebral disc degeneration itself, said Ximing Xu, professor in the Department of Orthopedic Surgery in Changzheng Hospital, and co-lead author of the study

One proposed solution is to administer dopamine directly to the brain, bypassing the need for its enzymatic conversion from levodopa

Some people may experience mild digestive changes like bloating or gas when first starting a supplement