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Several fungi inhabiting the woody tissues were shown to be causal agents of the esca disease complex (Bertsch et al., GSTs and the ratio of GSSG to total glutathione were suggested as early indicators of the presence of the esca disease in grapevine canes (Valtaud et al., 2009

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No freezing reconstituted peptides causes ice crystal formation that physically disrupts peptide structure, leading to irreversible aggregation and loss of biological activity