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The brain, mainly the hypothalamus, integrates these gut-derived signals, along with others, to coordinate the regulation of food intake, energy expenditure, and glucose homeostasis 14,15

Nevertheless, since the risk of cardiovascular and renal events will remain even with the use of GLP-1RA, there is a great deal of clinical interest in its combined use with SGLT2i and finerenone (Table 4)

This adaptable approach allows you to test market response without significant upfront investment, making it easier to adjust to evolving consumer trends and demands

Nishioka S, Takayama M, Watanabe M, Urusihara M, Kiriya Y, Hijioka S