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Drugging this type of GPCR with small molecules has its challenges say Jeff Finer, chief executive of Septerna, a biotech based in south San Francisco, US

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J Biochem Bioph Meth 64 , 207215, doi:10.1016/j.jbbm.2005.08.001 (2005)

Immune Reactivity: The FDA has previously flagged concerns that compounded peptides like BPC 157 carry risks of triggering unexpected immune or allergic reactions