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A study published in 2023 found that GLP-1 medications may help reduce inflammation and strengthen the gut lining in people with UC, though it notes that most of the evidence so far comes from animal and lab-based studies, not large trials in people

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Metabolic dysfunction creates an inflammatory, insulin-resistant, pressure-elevated environment that the brain cannot escape

The FDA has flagged emideltide/DSIP in a compounding safety-risk context because of insufficient safety information and concerns involving peptide impurities and immunogenicity, while existing human studies are too small and short-term to reliably assess long-term adverse effects