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Landmark Ed
Ipamorelin is a selective growth hormone secretagogue that activates the ghrelin receptor (GHS-R) in the pituitary
Paradoxically, whilst long-term weight loss typically improves joint health and reduces osteoarthritis symptoms (as noted in NICE NG226), the transition period may be associated with adjustment-related discomfort
Biliary complications (cholelithiasis, cholecystitis) represent a class effect attributable to reduced gallbladder motility, with incidence approximately 1.5-2.5-fold higher than placebo in long-term trials
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