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7 Shocking Mechanisms: How Biotin Triggers Acne Breakouts 1

Peroxynitrite is highly toxic to neurons and causes hyper-excitability of the central nervous system, a process known as "kindling." This leads to autonomic nervous system dysfunction (dysautonomia), sensory overload, and severe cognitive deficits

Maeta M, Miura N, Tanaka H, Nakamura T, Kawanishi R, Nishikawa Y, et al

Retrograde Mitochondrial-Nuclear Signaling One interesting feature of MOTS-c biology is that MOTS-c seems to travel to the nucleus of cells under conditions of stress and alter the expression of nuclear genes that control antioxidant defences as well as metabolic programs