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While extremely rare, allergic reactions to components in the IV solution can occur
The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult rats
Epigenetically, it deacetylates H4K16ac, counteracting hMOF activity to promote chromatin condensation and ATG activation (such as ATG7, BECN1 , and LC3B )
Observations in murine models of GHRH gene ablation point to possible normalization of growth indicators, including body weight, bone length, and lean mass, with concurrent increases in pituitary RNA and GH mRNA levels
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