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Although the majority of desmoplastic/spindle cell melanomas demonstrate S100 protein and/or Sox10 immunoreactivity, partial/or complete loss of expression of these markers such as that observed in malignant peripheral nerve sheath tumors can be found, 20, 21 especially in metastatic cases
10.1016/0003-2697(85)90174-5 Bergethon PR
The authors examined whether TB-500 may soften this signaling and suggested that the peptide may raise levels of miR-146a
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