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Access this article Similar content being viewed by others Abbreviations AAPH: Hydrochloride 2,2-azobis-2-amidinopropane AIDS: Acquired immunodeficiency syndrome ARE: Antioxidant response element CAT: Catalase Cu/Zn-SOD: Copper/zinc-superoxide dismutase DIVEMA: Divinyl ether and maleic anhydride DNA: Deoxyribonucleic acid EC-SOD: Extracellular-superoxide dismutase Fe-SOD: Iron-superoxide dismutase FIV: Feline immunodeficiency virus GPx: Glutathione peroxidase H 2 O 2 : Hydrogen peroxide HIV: Human immunodeficiency virus HO: Hydroxyl radical Mn-SOD: Manganese-superoxide dismutase Nrf2: Transcription factor nuclear-factor-E2-related factor O 2 - : Superoxide anion radical PEG: Pegylated PMA: Phorbol 12-myristate 13-acetate ROS: Reactive oxygen species SOD: Superoxide dismutase REFERENCES Davies KJA
This failure is largely due to testing exclusively on cancer cell lines grown in liquid medium, a condition that predicts in vivo efficacy to anticancer drugs worse than cell culture in 3D gels [4, 5] and is far from adequately reflecting the therapeutic responsiveness of cancers within their native microenvironment [2, 3]
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Place a barrier (cloth, paper towel) between the cold pack and the vial to prevent direct contact and accidental freezing
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