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La investigacin se orient a derivados de la florizina109, obtenindose compuestos con potente selectividad a SGLT2 con mayor estabilidad, mejor biodisponibilidad y con adecuada tolerancia dando origen a este nuevo grupo de frmacos inhibidores selectivos de SGLT2 (ISLGT2), con principios teraputicos totalmente diferente al de otros hipoglicemiantes110
Glutamine and cancer: cell biology, physiology, and clinical opportunities
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