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The most commonly reported side effects in Phase 2 trials were gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, which were generally mild to moderate and tended to improve over time
Compared to GLP-1 Agonists: Weight management peptides like semaglutide and tirzepatide have demonstrated weight loss efficacy superior to AOD-9604 in clinical trials, but they also have distinct side effect profiles
Many women experience: Perimenopause or menopause-related weight gain , especially around the midsection Decreased muscle mass , which lowers daily calorie burn Insulin resistance , making it harder for the body to use glucose efficiently Increased cravings , driven by fluctuating estrogen and progesterone levels Semaglutide addresses these challenges at their root by regulating appetite, reducing blood sugar spikes, and promoting fat loss
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