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In STEP 1, the phase 3 trial that led to semaglutide's approval for obesity, participants lost about 15% of their body weight over a year
In simple terms, it is studied for its ability to signal fat cells to release and burn stored fat while leaving blood sugar regulation largely untouched
The ability of antagonists to inhibit growth and inflammation suggests that they could be beneficial in treating these other disorders characterized by similar pathophysiological mechanisms
Symptoms included flushing, nausea, headaches, or fatigue
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