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Train in the 6-12 rep range with weights heavy enough to challenge the muscle while maintaining controlled form, as this provides the optimal stimulus for muscle preservation during a caloric deficit

They cause very similar side effects since both affect gut hormonesprimarily nausea, diarrhea, constipation, and reduced appetite

Insurance coverage Many health insurance plans do not cover weight loss medications, or they may have strict rules

Therefore, in cases of diabetes (both T1DM and T2DM), acromegaly and liver failure, a thorough understanding of normal physiology and pathophysiology will certainly help the treating physician to make the right decisions on how to intervene and improve metabolism for the benefit of patients