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doi: 10.1016/j.isci.2022.105717 74 OmoriKKatakamiNYamamotoYNinomiyaHTakaharaMMatsuokaTAet al
Neurotransmitter for Alzheimer's Disease Alzheimer's disease (AD) is the most common form of dementia, leading to cognitive decline and memory loss
Immunoblot analysis For detection of Gclc (Santa Cruz Biotechnology sc-390811), Pdha-1 (Abcam ab168379), DRP1 (Abcam ab184247), eIF4E (Abcam ab33766), p-eIF4E (Abcam ab76256), 4E-BP1 (Cell signaling 9452), p-4E-BP1 (Cell signaling 2855), DRP1 (Abcam ab184247), mTOR (Cell Signaling 2972), p-mTOR (Ser2448) (Cell Signaling 2971), p70 S6 (Cell Signaling 9202), p-p70 S6 (Thr421/Ser424) (Cell Signaling 9204), 15 10 6 cells were lysed with lysis buffer (CST 9803S) and protein/phosphatases inhibitors as per manufacturers protocol and blotted as described 44
In preclinical research, its been studied for its ability to promote angiogenesis (new blood vessel formation), support collagen organization, and modulate inflammation at the site of injury
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