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Berberine, an isoquinoline alkaloid from Berberis spp., has demonstrated promising antioxidant activity via promoting heme oxygenase-1 (HO-1) expression, activating Nrf2/AMPK/SIRT1 signaling, inhibiting the NLRP3 inflammasome, balancing glutathione levels, and regulating mitochondrial redox processes (Sunhe et al., 2024
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By regulating appetite and improving glucose metabolism, it helps individuals reduce body weight more effectively than traditional medications
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