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The most common side effects of this class of drugs are related to the gastrointestinal system: nausea, heartburn, vomiting, dyspepsia, diarrhoea, obstruction, and abdominal pain [26]
Impaired mitophagy in AD contributes to the accumulation of dysfunctional mitochondria and exacerbates A and hyperphosphorylated tau pathology
No, not in clinically meaningful ways
Some of these mechanisms focus on producing reactive oxygen species, glutathione depletion, plasmid curing inhibition, efflux pump inhibition, and resistance enzyme inhibition 46,47
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