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(Torbey, 2019) [2] Phenobarbital may increase the risk of valproic acid-induced hyperammonemia (as a result of hepatic enzyme induction by phenobarbital)
Discussion Key Study Findings The findings from the NMA support the clinical effectiveness and safety of tirzepatide compared with semaglutide and liraglutide, for multiple clinical outcomes considered in the management of obesity and overweight in patients without T2D, including weight reduction and cardiometabolic risk factors, such as waist circumference, lipids, blood pressure and glycaemic parameters
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