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MT-I vs MT-II: Melanotan I (afamelanotide) is more selective for MC1R, so it delivers the tanning effect with far less of the appetite-suppression and spontaneous-erection activity that MT-II produces at MC3/MC4 receptors but it is generally used more frequently to reach the same pigmentation [2]
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Side effects often appear during the early weeks of treatment or after dose increases
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