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A safe weight-management plan should track more than weight, including: Waist size Blood pressure Blood sugar Sleep Energy Mobility Long-term disease risk When to Talk to a Primary Care Provider Patients should schedule a medical visit if weight gain continues despite lifestyle changes, or if weight gain comes with fatigue, increased thirst, snoring, joint pain, irregular periods, high blood pressure, high cholesterol, or rising blood sugar

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An approved SC formulation with its own patent protection extending beyond the IV formulation patents combined with a clinical program demonstrating non-inferiority to IV pembrolizumab, would execute a classic product hop that positions Merck to transition the market to a formulation that biosimilar IV competitors cannot automatically substitute for