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doi:10.1038/aja.2011.64

Long-term metformin use can also be associated with lower vitamin B12 levels

Type IV DGK, which includes the iota and zeta isoforms, contain two C1 domains followed by a MARCKS homology domain [ M yristoylated A lanine- R ich C K inase (PKC) S ubstrate], a catalytic domain, four ankyrin repeats, and a C-terminal PDZ-binding site