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Glutathione synthetase Glutathione synthetase ( GSS ) (EC 6.3.2.3) is the second enzyme in the glutathione (GSH) biosynthesis pathway

However, after irradiation, GPx1-KO and wild-type mice exhibited almost similar levels of intestinal GPx activity, and this was due to the radiation-induced compensatory upregulation of GPx2 in GPx1-KO mice

Animal studies have shown that UC-MSCs could migrate to the kidneys to effectively repair renal dysfunction by reducing proteinuria, serum creatinine and urea nitrogen levels and increasing creatinine clearance in DKD rats (225)

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