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In recent years, independent research groups have begun to replicate some of these findings, adding credibility to the Zagreb team's extensive work
The compound failed its Phase IIb obesity endpoint in 2007, and Metabolic Pharmaceuticals terminated clinical development the same year
Because indomethacin is an inhibitor of prostaglandin synthesis, its mode of action may be due to a decrease of prostaglandins in peripheral tissues
The third approach combines lifestyle modifications established during treatment with strategic supplementation
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