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From reproductive health to metabolism and brain function, even small imbalances can create noticeable symptoms

Together, these mechanisms converge to prime melanogenesis, augment skins antioxidant defenses, and condition epidermal structures to better withstand UV exposure while facilitating a more uniform tanning response

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Similarly, recent studies in DS individuals suggest that epigenetic deregulation of several genes could not only account for CHD (Serra-Juh et al., 2015), but also for other complications such as learning and memory deficits (Dekker et al., 2014) or accelerated aging (Horvath et al., 2015), but how much of this results from in utero exposure is still unclear