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Semaglutide is a GLP-1 receptor agonist, a type of drug that mimics the GLP-1 hormone to regulate insulin, control blood sugar, reduce appetite, and promote weight loss

Osteoblast number on the surface of trabecular bone was observed by a histological analysis that demonstrated a significant increase after 16 weeks of exendin-4 use in OVX rats (32)

According to John Hopkins Medicine, some patients dont lose weight with GLP-1 medications while others cant tolerate them for extended periods

Accordingly, GLP-1 RA treatment has been shown to directly or indirectly improve cardiometabolic risk factors that characterise diabetes and obesity, and which play central roles in the development or exacerbation of CVD, including HF