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Second, current experiments rely on standardized animal models and do not fully reflect clinical heterogeneity, including differences in injury level, severity, and comorbidities and lack validation in human tissue samples
Finally, some examples in which these natural features of human RBCs can be further exploited to engineer RBCs by the encapsulation of drugs, metabolites, or target proteins are reported
Neurological and biochemical testing Neurological and biochemical characteristics of the patients are given in Supplementary Table 2
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