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Human adult dermal fibroblasts incubated with GHK-Cu at concentrations of 0.01, 1, and 100 nM demonstrated increased production of both elastin and collagen, with all concentrations increasing TIMP1 expression and low concentrations enhancing MMP1 and MMP2 gene expression

Previous studies on the single exogenous application of Pro have successfully alleviated stresses that include salinity and metal toxicity (Singh et al., 2015