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In obese mouse models: Animals treated with 5-Amino-1MQ lost significant fat mass compared to controls Effects were most pronounced in visceral adipose tissue the metabolically dangerous fat around organs No cardiovascular toxicity or significant off-target effects were observed at research doses Body weight decreased without appetite changes, suggesting the mechanism was purely metabolic Human data is limited this is still a research compound

Charlotte is a board-certified physician assistant and aesthetic injector specializing in neuromodulators, dermal fillers, and energy-based devices

2019 Jun Merav Jacobson Bensky, Irit Ayalon-Dangur, Roi Ayalon-Dangur, Eviatar Naamany, Anat Gafter-Gvili, Gideon Koren, Shachaf Shiber

N Engl J Med