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NADPH oxidases are considered as the major producers of O 2 in the vasculature, and moreover, they are regarded the main source of kindling radicals that trigger the activation of additional ROS sources, e.g., via eNOS uncoupling [63]

Crucially, this deficiency strongly correlated with the severity of the patients' fatigue, autonomic dysfunction, and neurocognitive symptoms

STUDYA small study (N=60) compared holding one preprocedure dose of a GLP-1 agonist (hold group) to not holding it (continuation group) in patients undergoing EGD with or without colonoscopy

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