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J Alzheimers Dis 78(4):12591272

When you eat, your gut releases GLP-1 as part of the normal digestion process to help signal fullness and regulate blood sugar

Comparative Mechanisms with Other Agents Compared with metformin, which improves insulin sensitivity primarily through hepatic and muscular pathways, GLP-1 RAs act centrally and peripherally to influence appetite, glucose metabolism, and systemic inflammation