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Ischemic stroke was obtained from MEGASTROKE consortium (34,217 cases and 406,111 controls) [25], the UK Biobank (7961 cases and 384,003 controls), and Finngen Biobank (10,551 cases and 208,241 controls) [26]
In Phase 2 clinical trials, patients showed progressive, dose-dependent weight loss of up to 24.2% of body weight with a 12 mg weekly dose
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