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Typical titration schedule in trials: Start at 2 mg weekly Increase every 4 weeks: 2 mg 4 mg 6 mg 9 mg or 12 mg (depending on target dose) This means it takes 3-4 months to reach the maximum dose Meaningful weight loss becomes apparent after reaching therapeutic doses and maintaining them for several weeks

who wasn't involved in the study, told Live Science

Last reviewed: June 22, 2026 Last updated: June 22, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations