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GLP-1R activation inhibits NF-kB through a series of complicated actions inside the cell, but ultimately for our purposes this leads to the downregulation of multiple inflammatory cytokines, including but not limited to Tumor Necrosis Factor Alpha, (TNF-a) Interleukin 6 and 1-beta (IL6 and IL-1b) and multiple others
Vincent, A., Benzo, R.P., Whipple, M.O
MRI 3 months post-treatment demonstrated no evidence of local or regional recurrence
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