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& Starodubova, A

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Mounjaro (tirzepatide) works on both GLP-1 and GIP receptors and has shown greater average weight loss in trials (around 21% on the highest dose over 72 weeks compared with 15% for Wegovy 2.4 mg, or 21% on the new Wegovy 7.2 mg dose)

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Metabolites play a key role, with prior studies having shown that the metabolites lactate, pyruvate, glutamine, and serine each support distinct stages of metastasis

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Most adverse events were mild for all three treatments, and all events except one had an outcome of recovered/resolved

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