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Preventive approaches include: Gradual dose titration: Following FDA-recommended titration schedules (starting at 2.5 mg weekly and increasing every 4 weeks) helps moderate the rate of weight loss, potentially reducing gallstone risk compared to aggressive dosing
JCI Insight 8 , e164921 (2023)
While pregnancy rates have not been precisely measured in clinical trials, reproductive health experts recommend using backup contraception methods or switching to long-acting reversible options when taking semaglutide injections
This concern is understandable, particularly as these treatments become more widely used
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