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In a double-blind clinical trial in Denmark, 52 patients (mean age, 50.2 years) with verified bile acid diarrhea received either one daily subcutaneous injection of liraglutide (increasing from 0.6-1.8 mg per day over 3 weeks) or standard-of-care colesevelam (three capsules of 625 mg twice daily) for 6 weeks following one run-in week with no treatment
doi: 10.1016/j.ejphar.2012.12.012 156 PaudelY
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Results FoB and MZB exhibit distinct glutathione-based redox dependencies To dissect the redox state of MZB and FoB in relation to the main antioxidant GSH, we studied the expression of Gclc , which is necessary for GSH synthesis 24 , in isolated MZB and FoB from spleens of C57BL/6J (B6 or wild-type) mice
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