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When hydroxocobalamin is given in high doses (such as during cyanide poisoning treatment), unique effects can be observed: patients often experience a transient reddening of the skin or mucous membranes and a reddish discoloration of the urine due to drug excretion

There are other non invasive treatments available for individuals who have weakness, instability, or have a high fall risk

The preservation of nicotinamide substrate drastically increases the efficiency of the NAD+ salvage pathway

Some research suggests low vitamin B12 levels are associated with higher body weight, but more research is needed in this area