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It is of interest to note that low AIP expression does not associate with resistance to pasireotide (61), the SS analog with the highest affinity for SSTR5, suggesting that AIP is not involved in the signal transduction of this specific SSTR subtype
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The proportion of patients achieving NASH resolution in the absence of fibrosis progression was 40%, 36%, and 59% for the 0.1, 0.2, and 0.4 mg semaglutide arms, respectively, whereas the corresponding rate in the placebo arm was 17% (Newsome et al., 2021)
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