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Amylin is secreted at the same time as insulin by cells in the pancreas
This conformation may also be representative of the peptide agonist conformation of GCGR and other class B GPCRs, although previous models of GLP-1R suggested a more tilted conformation of the ECD relative to the plane of the membrane in the GLP-1-bound state 23,24
As the market expands, it is essential to ensure that convenience does not overshadow the need for patient engagement, proper use, and safety awareness
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