semaglutide and heart issues boosts health, weight loss but may lead to gut problems Cardiovascular outcomes of semaglutide and

Future umbrella reviews should apply stricter screening or re-analyze based on primary studies

Ozempic was originally found to regulate blood sugar and is approved as a treatment for type 2 diabetes, while Wegovy was subsequently approved for weight loss and management

Acknowledgements This open-access review paper was supported by The project New Technologies for Translational Research in Pharmaceutical Sciences /NETPHARM, project ID CZ.02.01.01/00/22_008/0004607, is co-funded by the European Union, and the Erasmus+ Programme of the European Union, Key Action 2: Strategic Partnerships, Project no

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