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Pharmacology of valproic acid VPA potentiates -aminobutyric acid (GABA)ergic functions in some specific brain regions that are thought to be involved in the control of seizure generation and propagation by increasing both GABA synthesis and release [8]

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A review of studies concluded that the antioxidant properties of alpha lipoic acid could help manage neuropathic pain, though it also noted that clinical studies have been inconsistent with dosing and treatment protocols