does semaglutide cause thyroid issues and Hypothyroidism: What You Need to Know Semaglutide (Ozempic) carries FDA warnings

4 Mechanisms of hepatoprotection by GLP-1RAs as immune-metabolic modulators 4.1 Immunomodulatory mechanism of hepatic injuries by GLP-1RAs GLP-1RAs reduce inflammation, downregulate pro-inflammatory cytokines, and influence immune cell differentiation via the GLP-1 receptor, which alters macrophage polarization and inhibits fibrosis (Hammerich and Tacke, 2023)

These effects typically emerge within the first 4-8 weeks of consistent use, with continued improvements over 6-12 months

Because GLP-1s are delivered at home, they fall under pharmacy benefits but many payers only cover them for diabetes, not for weight loss

With proper diet and exercise, the results can be maintained for years to come