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PCOS also influences the hormones that regulate hunger and appetite
This calcium-dependent mechanism triggers rapid GH vesicle fusion and exocytosis independently of cAMP elevation, producing a fast, acute GH pulse that complements the transcriptionally-driven, cAMP-mediated GH synthesis supported by CJC-1295
Taking metformin, such as Glucophage tablets has been known to increase constipation, bloating, belly cramps and diarrhoea in some patients
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