In the TRIUMPH-4 Phase 3 results released last December, paresthesia was confirmed in 8.8% of the 9mg group and 20.9% of the 12mg group
Additionally, before and after each medication the thoracic fluid index was measured with bioimpedance cardiography (Physioflow Enduro, Manatec Biomedical, France) and blood samples were collected for the measurement of plasma bioactive renin, aldosterone and atrial natriuretic peptide (ANP)
Fenugreek ( Trigonella foenum-graecum ) seed is used traditionally to treat a range of conditions including high cholesterol levels, high glucose levels, and digestive problems, as well as promote breast milk production, relieve symptoms of premenstrual syndrome (PMS), and reduce menopausal symptoms
Long-acting, subcutaneously administered, PYY RA are undergoing early phase clinical trials as obesity treatments either alone or in combination with GLP-1 RA (Table 1, NCT02568306 and NCT03574584)