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Tirzepatide reduces body weight by increasing fat utilization via the central nervous system-adipose tissue axis in male mice

Among these drugs, glucagon-like peptide (GLP-1) drugs are strongly recommended by major diabetes treatment guidelines for their glucose-lowering effects, as well as for their weight-lowering, blood pressure-lowering, cardiovascular and renal protective effects

If gastrointestinal symptoms persist or worsen despite these measures, your prescriber may recommend adjusting your medication dose, slowing the titration schedule, temporarily reducing the dose, considering antiemetics if appropriate, or exploring alternative weight management strategies

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