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GLP-1 prescriptions for weight-loss In a separate analysis between 2020 and 2023, one HealthVerity closed claims dataset had more than 1.5 million patients who had at least one prescription for tirzepatide or semaglutide
Five distinct metabolic pathways activated simultaneously
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Many users find branded GLP-1s are not affordable and turn to lower cost sources, such as getting semaglutide made up by a compounding pharmacy (often requesting additions to the formula such as vitamin B12) a practice that is not recommended by the US FDA.13 This may decrease as the first generic versions of GLP-1 drugs become available, which started to get FDA approval in late 2024
