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In a rat model of ischemic stroke, administration of the herbal compound Salvia miltiorrhiza extract modulated gut microbiota composition, reduced infarct size, and decreased markers of inflammation and oxidative stress, indicating a gut-mediated neuroprotective effect (Wu J

Tang LJ, Luo XJ, Tu H, Chen H, Xiong XM, Li NS, et al

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107 GLP-1s ability to mediate the incretin effect is its most studied and significant physiological effect due to the use of GLP-1 analogues (exenatide and liraglutide, lixisenatide, dulaglutide, albiglutide and semaglutide) in T2D treatment