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Eur Heart J 44(39):40434140 Neves JS, Leite AR, Mentz RJ, Holman RR, Zannad F, Butler J et al (2025) Cardiovascular outcomes with exenatide in type 2 diabetes according to ejection fraction: the EXSCEL trial
Additional tests may include luteinising hormone (LH), follicle-stimulating hormone (FSH), prolactin, and in some cases sex hormone-binding globulin (SHBG) Psychological assessment : Screening for depression, anxiety, or relationship difficulties Lifestyle modifications remain first-line management and complement pharmacological diabetes treatment
Astrocytes release free fatty acids (FFAs) from lipid droplets, and the released fatty acids enter the mitochondria and bind to carnitine to form LCACs, the accumulation of which leads to mitochondrial dysfunction in astrocytes and exacerbates neuronal damage [115]
Omega-3 fatty acid intake may have also reduced the risk of progression to kidney failure in participants who did not receive a kidney transplant, but there was not enough data to draw a solid conclusion
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