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[3] Semaglutide works by mimicking the action of the naturally occurring hormone GLP-1, which is released from the intestine in response to food intake
Short courses (typically 510 days) are usually well-tolerated even without major dosing adjustments, while longer courses may warrant closer monitoring or temporary changes to tirzepatide frequency
Nitric oxide-dependent endothelial function is unaffected by allopurinol in hypercholesterolaemic subjects
It is given once a week beneath the skin
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